Background

35-year- old male, presented with left second toe swelling.  MRI showed a solid soft tissue mass measuring 4.1 x 2.8cm, showing moderate homogenous enhancement. Trucut biopsy sent for histopathological examination.

Microscopy 

Fig.1a; H&E; 20x

Fig.1b; H&E; 20x

Biopsy showed a high grade tumor with biphasic pattern. One component was of a high-grade sarcoma [Fig.1a] and intimately admixed were epithelial components [Fig.1b] in the form of glands and solid nests.

Fig.1c; TLE-1

Fig.1d; EMA

Immunohistochemistry revealed TLE, EMA & CK positivity [Fig.1c&d].

Final Impression: Biphasic Synovial Sarcoma.

Contributed by: Dr. Anila Sharma

Compiled by: Dr. Ankur Kumar & Dr. Himanshi Diwan

In case of queries, email us at: kumar.ankur@rgcirc.org

Soft tissue tumors Synovial sarcoma

Last modified: 05/06/2021